Clinical Studies
Current Clinical Research Projects
A list of clinical research studies in progress can be found below listed by the area of disease/condition. For further information on any of these studies, please follow the links provided, or contact the research department on 01691 404139/4354.
If you would like more information about taking part in a clinical trial, or to search for a clinical trial relevant to you, visit the NHS Clinical Trials Gateway website https://www.ukctg.nihr.ac.uk/home/
Rheumatology research
Our metabolic bone service is undertaking an assessment study of bone health within the clinical setting.
Sports Knee research
We are recruiting patients to a study of cellular therapy for me defects ACT 1); a study looking at the relationship between activity levels and knee function and the ASCOT trial, now in follow-up, which compares treatment with the patient's cartilage cells versus their mesenchymal stem cells for knee cartilage defects. other sports injury studies relate to the spontaneous healing of articular cartilage and a follow-up study of a fixation method for repairing meniscal cartilage.
Arthroplasty research (Joint Replacement)
PICO 7 Vs PICO 14 - this study is currently recruiting patients and is examining whether an advanced wound dressing can work over a seven-day period rather than two weeks.
We have a number of research studies looking at the long-term performance of different types of hip and knee replacement.
In addition to arthroplasty studies which are currently recruiting patients, the long-term nature of joint replacement means that we have another seven studies carefully evaluating the long-term performance and safety of hip and knee replacements.
Young Adult Hip
A current study is examining the relationship between data analysis findings and rotational deformities.
Foot & Ankle research
The ACTIVE trial looking at cellular treatments for ankle joint injuries.
Muscle Disorders research
There is an extensive programme of research relating to muscle disorders particularly in children with the ATL1102 Antisense trial for boys with Duchenne muscular dystrophy; hydrotherapy trial for children with Duchenne muscular dystrophy multiple studies looking at Spinal muscular atrophy.
Children's Orthopaedic research
A current study is examining the function of the to be a less posterior muscle in controlling foot posture in young people with cerebral palsy and also examining how the function of this muscle changes in older people.
We are participants in the Big BOSS study looking at the treatment of severe slips of the upper capital epiphysis which is a serious condition affecting the hip in children. This follows on from our participation in cpBOSS which looked at the treatment of children with cerebral palsy.
Spinal Injuries research
The Midland Centre for Spinal injuries is taking part in national (DISCUS), International (EMSCI) and locally generated research both adults and children spinal injuries.
Gait Laboratory research
The gait laboratory (ORLAU) has a number of studies ongoing looking at the properties of the calf muscle during walking; intelligent functional electrical stimulation for restoring our movement in people with tetraplegia and also rehabilitation for patients with Fascio-Scapulo-humeral dystrophy.