Clinical Studies

A list of open research studies at RJAH are listed below. For more details on taking part in research, see our Patients & Public page. You can also contact the Research Department by email at rjah.researchoffice@nhs.net, or phoning 01691 404142/404210.

For research occurring elsewhere, please use the NIHR’s Find a Study page.

Area

Local project number

Project short title

Project site status*

Anaesthetics

RL1 749

PQIP - Perioperative Quality Improvement Programme

Closed to recruitment - in follow up

 

RL1 872

ALLAY - Study Assessing Pain Relief After Replacement of the Knee

Open

Arthroplasty

RL1 840

Arthrosamid injection for knee OA

Closed to recruitment - in follow up

RL1 708

ATTUNE 10008: Long term follow-up from 10004

Closed to recruitment - in follow up

RL1 729

ATTUNE® Revision - Complex Primary in Total Knee Arthroplasty Population

Closed to recruitment - in follow up

RL1 564

BioGuard - Investigation of Taperloc Stems With BioGuard Coating in Cementless Total Hip Arthroplasty

Closed to recruitment - in follow up

RL1 731

ChALK - CHaracterising the relationship between Activity Level and Knee function

Open

RL1 728

Clinical Evaluation of ATTUNE® Revision - RTKA population

Closed to recruitment - in follow up

RL1 674

RECAP - Clinical evaluation of Recap Resurfacing and Recap Magnum Hips

Closed to recruitment - in follow up

RL1 463

Optektrak - Evaluation of the Optetrak Knee System

Closed to recruitment - in follow up

RL1 906

HIPPY - Hip Implant Prosthesis Programme for the Younger total hip replacement patient

Open

RL1 844

STAR - Support and treatment after replacement: follow-up study

Closed to recruitment - in follow up

RL1 894

ICONIC - Malignant neoplasms of bone and articular cartilage

Open

RL1 786

PICO 7 vs 14 for Revision Hips and Knees

Open

RL1 893

SYNC-01 - Phase Four: Validation of Final Questionnaire

Open

RL1 879

Tint10 - Follow up of titanium modular revision hip system

Open

Cell therapy

RL1 461

ASCOT - Autologous Stem Cells, Chondrocytes or the Two?

Closed to recruitment - in follow up

RL1 418

A study of ACI vs alternative treatments

Open

RL1 774

ACTIVE - ACI vs existing treatments

Closed to recruitment - in follow up

Foot & Ankle

RL1 739

HyperEx post market surveillance

Closed to recruitment - in follow up

RL1 901

Incidence of subtalar joint fusion after isolated ankle fusion

Open

RL1 683

UK Infinity Post-Market Clinical Follow-up Study

Closed to recruitment - in follow up

RL1 849

Stryker Retrospective Data Collection

Closed to recruitment - in follow up

RL1 803

Wright Foot and Ankle Post-Merket Observational Study

Closed to recruitment - in follow up

RL1 911

UK ADAPTIS post market surveillance

Open

Hand & Upper Limb

RL1 905

Comparative Analysis of Anatomic Shoulder Arthroplasty, Hemiarthroplasty, and Reverse Shoulder Arthroplasty

Open

RL1 900

Elbow Arthroplasty Activities (EAA)

Open

RL1 841

POWER: Physiotherapy for patients awaiting rotator cuff repair

Closed to recruitment - in follow up

RL1 828

SOFFT: Simple Olecranon Fracture Fixation Trial

Closed to recruitment - in follow up

RL1 867

Assessment of a robotic exoskeleton for upper limb rehabilitation

Open

Imaging

RL1 878

Ultrasound - MRI fusion guided Botox muscle injections

Open

Laboratories

RL1 735

Developing allogeneic musculoskeletal therapies

Open

RL1 462

Developing new therapies for orthopaedics and spinal cord injury

Open

RL1 566

Monoclonal antibodies (mAbs) against nebulin for studies of nemaline myopathy

Open

RL1 367

MRC Biomarkers - Arthritis and cartilage repair study

Open

RL1 513

Orthopaedic Tissues for Research (OTFR)

Open

RL1 889

SELECT - Investigating the potential of T cells isolated from juvenile thymuses for the development of allogeneic therapies for autoimmune conditions

Open

RL1 829

Spine Microbiome

Closed to recruitment - in follow up

RL1 556

Spinal Muscular Atrophy (SMA) and stem cells

Open

RL1 512

Tissue biomarkers for spinal cord injury

Open

Metabolic

RL1 896

Advantage Bone

Open

RL1 842

The Assessment of Bone Health in a Clinical Setting

Open

RL1 899

OsBONE

Open

Musculoskeletal Services (MSST)

RL1 927

D-MAPP

Open

Neurology

RL1 874

SMA Review

Open

Neuromuscular

RL1 875

A study of ATL1102 in boys with DMD who cannot walk independently and need wheelchair assistance

Closed to recruitment - in follow up

RL1 810

Givinostat51 (Italfarmaco)

Closed to recruitment - in follow up

RL1 921

HERCULES - Efficacy and Safety of Once Daily Mexiletine Treatment in Patients with Myotonic Dystrophy Type 1 and Type 2

Open

RL1 877

Hydrotherapy in DMD

Closed to recruitment - in follow up

RL1 809

Quantification of head and trunk control for children

Closed to recruitment - in follow up

RL1 856

Adult SMA REACH Study

Open

RL1 754

Improving standards of care and Translational Research in Spinal Muscular Atrophy

Open

RL1 902

NIHR BioResource - Rare Diseases

Open

ORLAU

RL1 863

Best-practice rehabilitation for Facioscapulohumeral dystrophy (FSHD)

Open

RL1 550

Collection of normal reference data for understanding human movement

Open

Paediatric Physiotherapy

RL1 908

ROBUST - Strengthening programme for ambulant adolescents with cerebral palsy

Open

RL1 907

SPELL - Stretching programme for ambulant children with cerebral palsy

Open

Paediatric Surgery

RL1 885

The Big BOSS Study

Open

Physiotherapy

RL1 871

BOOST-IS - education and exercise programme for older adults with neurogenic claudication

Closed to recruitment - in follow up

 

RL1 909

Adelphi - SpA Extend 2024

Open

Rheumatology

RL1 919

EXPEDITE - Real world evidence of bimekizumab in axial spondyloarthritis

Open

RL1 910

TaILOR - Patient initiated follow up vs standard care

Open

RL1 651

UKIVAS

Open

Spinal Injuries

RL1 882

Arm cycling III

Open

RL1 845

DISCUS - Duroplasty for Injured Cervical Spinal Cord With Uncontrolled Swelling

Open

RL1 714

EMSCI - European Multicenter Study about Spinal Cord Injury

Open

RL1 831

Functional activity to improve trunk function

Open

RL1 815

Paediatric SCI and long-term Social Outcomes

Open

RL1 904

SCI Length of Stay Study (UK Arm)

Open

RL1 857

Upper-body aerobic exercise in the acute stage post spinal cord injury (HRUK)

Open

Sport Injuries

RL1 918

ACL-STARR – ACL Repair or Reconstruction: finding the best treatment for tears of the ACL

Open

Tumour Unit

RL1 793

ICONIC

Closed to recruitment - in follow up

RL1 755

Understanding Chordoma: A National Cohort Study

Closed to recruitment - in follow up

RL1 820

Artificial intelligence in the diagnosis of orthopaedic conditions

Open

RL1 913

What is a wide margin when resecting RCC metastasis to bone?

Open

Last updated: 29 December 2025

  • *Open: open to new participants

  • *Closed to recruitment – in follow up: the study is no longer taking new participants, but study activity is ongoing

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